A core mission of the U.S. Department of Energy's (DOE) Carbon Sequestration Program is to foster the development of commercially-ready technologies for CO2 capture and sequestration. R&D supported by the U.S. DOE is investigating alternatives to absorption for capturing CO2 that may achieve program goals. Membrane gas separation has a number of advantages, in that they are usually compact, have no moving parts, have low maintenance, and are highly reliable. In this assessment, alternative flowsheets incorporating membranes that may out-perform current technologies for CO2 capture were investigated. An initial screening study identified several novel integrations of membranes for IGCC applications.